Yayınlar

A. Long-Term Immunogenicity and Safety of a Homologous Third Dose Booster Vaccination with TURKOVAC

Sezer Z, Pavel STI, Inal A, Yetiskin H, Kaplan B, Uygut MA, Aslan AF, Bayram A, Mazicioglu M, Kalin Unuvar G, Yuce ZT, Aydin G, Kaya RK, Ates I, Kara A, Ozdarendeli A. Long-Term Immunogenicity and Safety of a Homologous Third Dose Booster Vaccination with TURKOVAC: Phase 2 Clinical Study Findings with 32-Week Post-Booster Follow-Up. Vaccines (Basel). 2024 Jan 29;12(2):140.

2024

doi: 10.3390/vaccines12020140.

Progress in Vaccine Development

Ozdarendeli, A. (2023). Crimean–Congo Hemorrhagic Fever Virus: Progress in Vaccine Development. Diagnostics, 13(16), 2708.

2023
Safety and immunogenicity of an inactivated whole virion SARS-CoV-2 vaccine, TURKOVAC, in healthy adults

Ozdarendeli, A., Sezer, Z., Pavel, S. T. I., Inal, A., Yetiskin, H., Kaplan, B., Uygut MA... & Kara, A. (2023). Safety and immunogenicity of an inactivated whole virion SARS-CoV-2 vaccine, TURKOVAC, in healthy adults: Interim results from randomised, double-blind, placebo-controlled phase 1 and 2 trials. Vaccine, 41(2), 380-390.

2023
Long-Term Results of Immunogenicity of Booster Vaccination against SARS-CoV-2 (Hybrid COV-RAPEL TR Study) in Turkiye

Ates, I., Batirel, A., Aydin, M., Karadag, F. Y., Erden, A., Kucuksahin, O., ….Ozdarendeli A….. & Kara, A. (2023). Long-Term Results of Immunogenicity of Booster Vaccination against SARS-CoV-2 (Hybrid COV-RAPEL TR Study) in Turkiye: A Double-Blind, Randomized, Controlled, Multicenter Phase 2 Clinical Study. Vaccines, 11(7), 1234.

2023
Plant-produced RBD and cocktail-based vaccine candidates are highly effective against SARS-CoV-2, independently of its emerging variants

Mamedov, T., Yuksel, D., Gurbuzaslan, I., Ilgin, M., Gulec, B., Mammadova, G., ... & Hasanova, G. (2023). Plant-produced RBD and cocktail-based vaccine candidates are highly effective against SARS-CoV-2, independently of its emerging variants. Frontiers in Plant Science, 14.

2023
Safety and immunogenicity of inactive vaccines as booster doses for COVID-19 in Türkiye

Omma, A., Batirel, A., Aydin, M., Yilmaz Karadag, F., Erden, A., Kucuksahin, O., .. Ozdarendeli, A.,. & Ates, I. (2022). Safety and immunogenicity of inactive vaccines as booster doses for COVID-19 in Türkiye: A randomized trial. Human Vaccines & Immunotherapeutics, 18(6), 2122503.

2022
Efficacy, Immunogenicity, and Safety of the Two-Dose Schedules of TURKOVAC versus CoronaVac in Healthy

Tanriover, M. D., Aydin, O. A., Guner, R., Yildiz, O., Celik, I., Doganay, H. L., …Ozdarendeli, A... & TURKOVAC Study Group. (2022). Efficacy, Immunogenicity, and Safety of the Two-Dose Schedules of TURKOVAC versus CoronaVac in Healthy Subjects: A Randomized, Observer-Blinded, Non-Inferiority Phase III Trial. Vaccines, 10(11), 1865.

2022
Preclinical studies on convalescent human immune plasma-derived exosome

Taşlı, N. P., Gönen, Z. B., Kırbaş, O. K., Gökdemir, N. S., Bozkurt, B. T., Bayrakcı, B., … Yetiskin, H., Kaplan, B., Islam Pavel S.T. I.,... Ozdarendeli, A, Cetin, M. (2022). Preclinical studies on convalescent human immune plasma-derived exosome: Omics and antiviral properties to SARS-CoV-2. Frontiers in immunology, 13, 904.

2022
A pilot study for treatment of severe COVID-19 pneumonia by aerosolized formulation of convalescent human immune plasma exosomes

Gül, F., GÖNEN, Z., Jones, O., Taşlı, N., ZARARSIZ, G., Ünal, E., Ozdarendeli, A... Uygut M.A…&Çetin, M. (2022). A pilot study for treatment of severe COVID-19 pneumonia by aerosolized formulation of convalescent human immune plasma exosomes (ChipEXO™). Frontiers in Immunology, 13.

2022
The Seroprevalence of Crimean-Congo Hemorrhagic Fever in Wild and Domestic Animals

Nurettin, C., Engin, B., Sukru, T., Munir, A., Zati, V., & Aykut, O. (2022). The Seroprevalence of Crimean-Congo Hemorrhagic Fever in Wild and Domestic Animals: An Epidemiological Update for Domestic Animals and First Seroevidence in Wild Animals from Turkiye. Veterinary Sciences, 9(9), 462.

2022
Development of an inactivated vaccine against SARS CoV-2

Pavel, S. T. I., Yetiskin, H., Uygut, M. A., Aslan, A. F., Aydın, G., İnan, Ö., ... & Ozdarendeli, A. (2021). Development of an inactivated vaccine against SARS CoV-2. Vaccines, 9(11), 1266.

2021
Development of a protective inactivated vaccine against Crimean–Congo hemorrhagic fever infection

Berber, E., Çanakoğlu, N., Tonbak, Ş., & Ozdarendeli, A. (2021). Development of a protective inactivated vaccine against Crimean–Congo hemorrhagic fever infection. Heliyon, 7(10), e08161.

2021
Immune responses in multiple hosts to Nucleocapsid Protein (NP) of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)

Karaaslan, E., Çetin, N. S., Kalkan-Yazıcı, M., Hasanoğlu, S., Karakeçili, F., Özdarendeli, A., ... & Doymaz, M. Z. (2021). Immune responses in multiple hosts to Nucleocapsid Protein (NP) of Crimean-Congo Hemorrhagic Fever Virus (CCHFV). PLoS Neglected Tropical Diseases, 15(12), e0009973.

2021
Development of a novel recombinant ELISA for the detection of Crimean-Congo hemorrhagic fever virus IgG antibodies

Gülce-İz, S., Elaldı, N., Can, H., Şahar, E. A., Karakavuk, M., Gül, A., …Ozdarendeli, A...  & Döşkaya, M. (2021). Development of a novel recombinant ELISA for the detection of Crimean-Congo hemorrhagic fever virus IgG antibodies. Scientific reports, 11(1), 5936.

2021
Production and characterization of nucleocapsid and RBD cocktail antigens of SARS-CoV-2 in Nicotiana benthamiana plant as a vaccine candidate against COVID-19

Mamedov, T., Yuksel, D., Ilgın, M., Gürbüzaslan, I., Gulec, B., Mammadova, G., Ozdarendeli, A, Yetiskin, H., Kaplan, B., Islam Pavel S.T. I., Uygut M.A., Hasanova, G. (2021). Production and characterization of nucleocapsid and RBD cocktail antigens of SARS-CoV-2 in Nicotiana benthamiana plant as a vaccine candidate against COVID-19. Vaccines, 9(11), 1337.

2021
Plant-produced glycosylated and in vivo deglycosylated receptor binding domain proteins of SARS-CoV-2 induce potent neutralizing responses in mice

Mamedov, T., Yuksel, D., Ilgın, M., Gurbuzaslan, I., Gulec, B., Yetiskin, H., Uygut M.A., Islam Pavel S.T. I.,Ozdarendeli A.. & Hasanova, G. (2021). Plant-produced glycosylated and in vivo deglycosylated receptor binding domain proteins of SARS-CoV-2 induce potent neutralizing responses in mice. Viruses, 13(8), 1595.

2021
Isolation and characterization of severe acute respiratory syndrome coronavirus 2 in Turkey

Pavel, S. T. I., Yetiskin, H., Aydin, G., Holyavkin, C., Uygut, M. A., Dursun, Z. B., ... & Ozdarendeli, A. (2020). Isolation and characterization of severe acute respiratory syndrome coronavirus 2 in Turkey. PloS one, 15(9), e0238614.

2020
Evaluation of the cell culture based and the mouse brain derived inactivated vaccines against Crimean-Congo hemorrhagic fever virus in transiently immune-suppressed (IS) mouse model

Pavel, S. T. I., Yetiskin, H., Kalkan, A., & Ozdarendeli, A. (2020). Evaluation of the cell culture based and the mouse brain derived inactivated vaccines against Crimean-Congo hemorrhagic fever virus in transiently immune-suppressed (IS) mouse model. PLoS Neglected Tropical Diseases, 14(11), e0008834.

2020
Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

Alm, E., Broberg, E. K., Connor, T., Hodcroft, E. B., Komissarov, A. B., Maurer-Stroh, S., ... & Pereyaslov, D. (2020). Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Eurosurveillance, 25(32), 2001410.

2020
Overview of zoonotic diseases in Turkey

Inci, A., Doganay, M., Özdarendeli, A., Düzlü, Ö., & Yıldırım, A. (2018). Overview of zoonotic diseases in Turkey: the one health concept and future threats, Turkiye Parazitolojii Derg. 42  39–80.

2018
Immunization of knock-out α/β interferon receptor mice against high lethal dose of Crimean-Congo hemorrhagic fever virus with a cell culture based vaccine

Canakoglu, N., Berber, E., Tonbak, S., Ertek, M., Sozdutmaz, I., Aktas, M., ... & Ozdarendeli, A. (2015). Immunization of knock-out α/β interferon receptor mice against high lethal dose of Crimean-Congo hemorrhagic fever virus with a cell culture based vaccine. PLoS neglected tropical diseases, 9(3), e0003579.

2015
Immunization of knock-out α/β interferon receptor mice against high lethal dose of Crimean-Congo hemorrhagic fever virus with a cell culture based vaccine

Canakoglu, N., Berber, E., Tonbak, S., Ertek, M., Sozdutmaz, I., Aktas, M., ... & Ozdarendeli, A. (2015). Immunization of knock-out α/β interferon receptor mice against high lethal dose of Crimean-Congo hemorrhagic fever virus with a cell culture based vaccine. PLoS neglected tropical diseases, 9(3), e0003579.titration of Crimean-Congo hemorrhagic fever virus. Journal of virological methods, 187(1), 26-31.

2015
Pseudo-plaque reduction neutralization test (PPRNT) for the measurement of neutralizing antibodies to Crimean-Congo hemorrhagic fever virus

Canakoglu, N., Berber, E., Ertek, M., Yoruk, M. D., Tonbak, S., Bolat, Y., ... & Ozdarendeli, A. (2013). Pseudo-plaque reduction neutralization test (PPRNT) for the measurement of neutralizing antibodies to Crimean-Congo hemorrhagic fever virus. Virology journal, 10, 1-7.

2013
The complete genome analysis of Crimean-Congo hemorrhagic fever virus isolated in Turkey

Özdarendeli, A., Çanakoğlu, N., Berber, E., Aydın, K., Tonbak, Ş., Ertek, M., ... & Kalkan, A. (2010). The complete genome analysis of Crimean-Congo hemorrhagic fever virus isolated in Turkey. Virus research, 147(2), 288-293.

2010
Genetic analysis of the M RNA segment of Crimean-Congo hemorrhagic fever virus strains in Turkey

Ozdarendeli, A., Aydin, K, Tonbak, S., Aktas, M., Altay, K., Koksal, ... & Kalkan, A. (2008). Genetic analysis of the M RNA segment of Crimean-Congo hemorrhagic fever virus strains in Turkey. Archives of virology, 153, 37-44.

2008
Crimean-Congo hemorrhagic fever virus: genetic analysis and tick survey in Turkey

Tonbak, S., Aktas, M., Altay, K., Azkur, A. K., Kalkan, A., Bolat, Y., ... & Ozdarendeli, A. (2006). Crimean-Congo hemorrhagic fever virus: genetic analysis and tick survey in Turkey. Journal of clinical microbiology, 44(11), 4120-4124.

2006